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Results for "

kidney hypoxia

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-17608
    Daprodustat
    5+ Cited Publications

    GSK1278863

    		 HIF/HIF Prolyl-Hydroxylase Cardiovascular Disease
    Daprodustat (GSK1278863) is an orally active hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor being developed for the treatment of anemia associated with chronic kidney disease.
    Daprodustat
  • HY-101277
    Vadadustat
    4 Publications Verification

    PG-1016548; AKB-6548

    		 HIF/HIF Prolyl-Hydroxylase Cardiovascular Disease
    Vadadustat (PG-1016548) is a titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor . Vadadustat is an erythropoiesis-stimulating agent and has the potential for anemia treatment in chronic kidney disease in vivo .
    Vadadustat
  • HY-111547
    M1001

    		HIF/HIF Prolyl-Hydroxylase Cancer
    M1001 is a weak hypoxia-inducible factor-2α (HIF-2α) agonist. M1001 can bind to the HIF-2α PAS-B domain, with a Kd of 667 nM. M1001 can be used in chronic kidney disease research .
    M1001
  • HY-149836
    3-MeOARh-NTR

    		Fluorescent Dye Others
    3-MeOARh-NTR is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection .
    3-MeOARh-NTR
  • HY-N1960
    Ophiopogonin A

    Ophiopogonin A is a natural steroid that can be found in Ophiopogon japonicus. Ophiopogonin A dose-dependently inhibits hemorrhagic shock (HS)-induced tissue damage and apoptosis. ophiopogonin A dose-dependently promotes the phosphorylation of ERK in HS kidney tissues and hypoxia-treated HK-2 cells .
    Ophiopogonin A
  • HY-149836A
    3-MeOARh-NTR chloride

    		Fluorescent Dye Others
    3-MeOARh-NTR chloride is an activatable imaging probe with high selectivity, and good stability. 3-MeOARh-NTR chloride possesses high selectivity and high signal-to-noise ratio for nitroreductase (NTR) detection, and serves as an efficient molecular tool for endogenous NTR detection .
    3-MeOARh-NTR chloride

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